Jeffrey Drebin, MD, PhD

Jeffrey Drebin, MD, PhD

Jeffrey Drebin, MD, PhD

Profile:

Dr. Drebin is the Chair of the Department of Surgery and Attending Surgeon on the Hepatopancreatobiliary Service. He is a surgeon and scientist that specializes in treating people with pancreatic cancer, gallbladder and bile duct cancers, liver cancer, and stomach cancer. Dr. Drebin studyies the molecular make-up of pancreas cancer to create better tools for diagnosis and prognosis. He is also developing ways to use the immune system to fight cancer. In addition to using immunotherapy, Dr. Drebin is also working on developing early detection methods, which could potentially prevent pancreas cancer.


Dr. Drebin’s MSK Profile


Publications:

  1. Buisman, FE, Galjart, B, van der Stok, EP, Balachandran, VP, Boerner, T, Drebin, JA et al.. Recurrence Patterns After Resection of Colorectal Liver Metastasis are Modified by Perioperative Systemic Chemotherapy. World J Surg. 2019; :. doi: 10.1007/s00268-019-05121-9. PubMed PMID:31410513 .
  2. Attiyeh, MA, Chakraborty, J, McIntyre, CA, Kappagantula, R, Chou, Y, Askan, G et al.. CT radiomics associations with genotype and stromal content in pancreatic ductal adenocarcinoma. Abdom Radiol (NY). 2019;44 (9):3148-3157. doi: 10.1007/s00261-019-02112-1. PubMed PMID:31243486 PubMed Central PMC6692205.
  3. McIntyre, CA, Pulvirenti, A, Lawrence, SA, Seier, K, Gonen, M, Balachandran, VP et al.. Neutrophil-to-Lymphocyte Ratio as a Predictor of Invasive Carcinoma in Patients With Intraductal Papillary Mucinous Neoplasms of the Pancreas. Pancreas. 2019;48 (6):832-836. doi: 10.1097/MPA.0000000000001342. PubMed PMID:31210665 .
  4. Newton, AD, Predina, JD, Shin, MH, Frenzel-Sulyok, LG, Vollmer, CM, Drebin, JA et al.. Intraoperative Near-infrared Imaging Can Identify Neoplasms and Aid in Real-time Margin Assessment During Pancreatic Resection. Ann. Surg. 2019;270 (1):12-20. doi: 10.1097/SLA.0000000000003201. PubMed PMID:31188797 .
  5. Karasic, TB, O'Hara, MH, Loaiza-Bonilla, A, Reiss, KA, Teitelbaum, UR, Borazanci, E et al.. Effect of Gemcitabine and nab-Paclitaxel With or Without Hydroxychloroquine on Patients With Advanced Pancreatic Cancer: A Phase 2 Randomized Clinical Trial. JAMA Oncol. 2019;5 (7):993-998. doi: 10.1001/jamaoncol.2019.0684. PubMed PMID:31120501 PubMed Central PMC6547080.
  6. Maggino, L, Malleo, G, Bassi, C, Allegrini, V, McMillan, MT, Borin, A et al.. Decoding Grade B Pancreatic Fistula: A Clinical and Economical Analysis and Subclassification Proposal. Ann. Surg. 2019;269 (6):1146-1153. doi: 10.1097/SLA.0000000000002673. PubMed PMID:31082914 .
  7. Creasy, JM, Goldman, DA, Gonen, M, Dudeja, V, O'Reilly, EM, Abou-Alfa, GK et al.. Evolution of surgical management of gallbladder carcinoma and impact on outcome: results from two decades at a single-institution. HPB (Oxford). 2019; :. doi: 10.1016/j.hpb.2019.03.370. PubMed PMID:31027875 .
  8. Rocheleau, AD, Melrose, AR, Cunliffe, JM, Klimek, J, Babur, Ö, Tassi Yunga, S et al.. Identification, Quantification, and System Analysis of Protein N-ε Lysine Methylation in Anucleate Blood Platelets. Proteomics. 2019;19 (11):e1900001. doi: 10.1002/pmic.201900001. PubMed PMID:30977292 .
  9. Gholami, S, Kemeny, NE, Boucher, TM, Gönen, M, Cercek, A, Kingham, TP et al.. Adjuvant Hepatic Artery Infusion Chemotherapy is Associated With Improved Survival Regardless of KRAS Mutation Status in Patients With Resected Colorectal Liver Metastases: A Retrospective Analysis of 674 Patients. Ann. Surg. 2019; :. doi: 10.1097/SLA.0000000000003248. PubMed PMID:30817353 .
  10. Narayan, RR, Goldman, DA, Gonen, M, Reichel, J, Huberman, KH, Raj, S et al.. Peripheral Circulating Tumor DNA Detection Predicts Poor Outcomes After Liver Resection for Metastatic Colorectal Cancer. Ann. Surg. Oncol. 2019;26 (6):1824-1832. doi: 10.1245/s10434-019-07201-5. PubMed PMID:30706231 PubMed Central PMC6511310.
  11. Lawrence, SA, McIntyre, CA, Pulvirenti, A, Seier, K, Chou, Y, Gonen, M et al.. Perioperative Bundle to Reduce Surgical Site Infection after Pancreaticoduodenectomy: A Prospective Cohort Study. J. Am. Coll. Surg. 2019;228 (4):595-601. doi: 10.1016/j.jamcollsurg.2018.12.018. PubMed PMID:30630087 .
  12. Narayan, RR, Creasy, JM, Goldman, DA, Gönen, M, Kandoth, C, Kundra, R et al.. Regional differences in gallbladder cancer pathogenesis: Insights from a multi-institutional comparison of tumor mutations. Cancer. 2019;125 (4):575-585. doi: 10.1002/cncr.31850. PubMed PMID:30427539 PubMed Central PMC6636637.
  13. Tufts, LS, Jarnagin, ED, Flynn, JR, Gonen, M, Guillem, JG, Paty, PB et al.. A perioperative multidisciplinary care bundle reduces surgical site infections in patients undergoing synchronous colorectal and liver resection. HPB (Oxford). 2019;21 (2):181-186. doi: 10.1016/j.hpb.2018.07.001. PubMed PMID:30077525 PubMed Central PMC6358518.
  14. Gagnière, J, Dupré, A, Gholami, SS, Pezet, D, Boerner, T, Gönen, M et al.. Is Hepatectomy Justified for BRAF Mutant Colorectal Liver Metastases?: A Multi-institutional Analysis of 1497 Patients. Ann. Surg. 2018; :. doi: 10.1097/SLA.0000000000002968. PubMed PMID:29995686 .
  15. Concors, SJ, Kirkland, ML, Schuricht, AL, Dempsey, DT, Morris, JB, Vollmer, CM et al.. Resection of gallbladder remnants after subtotal cholecystectomy: presentation and management. HPB (Oxford). 2018;20 (11):1062-1066. doi: 10.1016/j.hpb.2018.05.005. PubMed PMID:29887262 .
  16. Shabason, JE, Chen, J, Apisarnthanarax, S, Damjanov, N, Giantonio, B, Loaiza-Bonilla, A et al.. A phase I dose escalation trial of nab-paclitaxel and fixed dose radiation in patients with unresectable or borderline resectable pancreatic cancer. Cancer Chemother. Pharmacol. 2018;81 (3):609-614. doi: 10.1007/s00280-018-3519-6. PubMed PMID:29362902 .
  17. Maggino, L, Malleo, G, Bassi, C, Allegrini, V, McMillan, MT, Borin, A et al.. Decoding Grade B Pancreatic Fistula: A Clinical and Economical Analysis and Subclassification Proposal. Ann. Surg. 2018; :. doi: 10.1097/SLA.0000000000002673. PubMed PMID:29334556 .
  18. Ecker, BL, Vining, CC, Roses, RE, Maggino, L, Lee, MK, Drebin, JA et al.. Identification of Patients for Adjuvant Therapy After Resection of Carcinoma of the Extrahepatic Bile Ducts: A Propensity Score-Matched Analysis. Ann. Surg. Oncol. 2017;24 (13):3926-3933. doi: 10.1245/s10434-017-6095-9. PubMed PMID:28952140 .
  19. Maggino, L, Malleo, G, Bassi, C, Allegrini, V, Beane, JD, Beckman, RM et al.. Identification of an Optimal Cut-off for Drain Fluid Amylase on Postoperative Day 1 for Predicting Clinically Relevant Fistula After Distal Pancreatectomy: A Multi-institutional Analysis and External Validation. Ann. Surg. 2019;269 (2):337-343. doi: 10.1097/SLA.0000000000002532. PubMed PMID:28938266 .
  20. Puri, PM, Watkins, AA, Kent, TS, Maggino, L, Jeganathan, JG, Callery, MP et al.. Decision-Making for the Management of Cystic Lesions of the Pancreas: How Satisfied Are Patients with Surgery?. J. Gastrointest. Surg. 2018;22 (1):88-97. doi: 10.1007/s11605-017-3564-1. PubMed PMID:28875275 .
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