Jian Zheng

Jian Zheng

Jian Zheng, MD


The liver has always been an interest of mine. For the past decade, I have been a staunch advocate for hepatitis B and liver cancer outreach and co-founded Team HBV in 2006 which has steadily grown to over a dozen college chapters. Building on my passion to fight against liver cancer, my current research focuses on both primary and metastatic liver cancers. With the HPB team, we are evaluating novel tools to predict postoperative complications, recurrence and overall survival in these patients. For example, we are studying microRNA dysregulation and targeted genomic profile in patients with hepatocellular carcinoma and colorectal liver metastasis for diagnostic and prognostic purposes. We are also using quantitative image analysis of CT image of liver to predict presence of microvascular invasion and micrometastasis not visible to the naked eyes.

Funding Info:




  1. Liu, X, Fan, W, Lu, Z, Qin, Y, Yang, S, Li, Y et al.. Solvent Driven Reversible Phase Transition of Pillared Metal-Organic Framework. Chemistry. 2019; :. doi: 10.1002/chem.201900406. PubMed PMID:30786080 .
  2. Qian, B, Zheng, Z, Michailidis, M, Fleck, N, Bilton, M, Song, Y et al.. Mussel-inspired Self-healing Coatings Based on Polydopamine Coated Nanocontainers for Corrosion Protection. ACS Appl Mater Interfaces. 2019; :. doi: 10.1021/acsami.8b21197. PubMed PMID:30785720 .
  3. Ou, X, Cao, L, Liang, X, Zheng, F, Zheng, HS, Yang, X et al.. Fabrication of SnS2/Mn2SnS4/Carbon Heterostructures for Sodium-Ion Batteries with High Initial Coulombic Efficiency and Cycling Stability. ACS Nano. 2019; :. doi: 10.1021/acsnano.9b00375. PubMed PMID:30785716 .
  4. Zheng, Y, Zhang, J, Cheng, X, Xu, X, Zhang, L. The Wolff-Rearrangement Reaction of Oxidatively Generated α-Oxo Gold Carbenes: An Effective Approach to Silylketenes. Angew. Chem. Int. Ed. Engl. 2019; :. doi: 10.1002/anie.201814018. PubMed PMID:30785666 .
  5. Zheng, L, Wang, L, Ren, G, Zhang, R, Liang, S, Wang, B et al.. Patients-related factors associated with successful cannulation of trainees during hands-on ERCP training. Dig Endosc. 2019; :. doi: 10.1111/den.13377. PubMed PMID:30785645 .
  6. Fan, X, Wang, H, Sun, L, Zheng, X, Yin, X, Zuo, X et al.. Fine mapping and subphenotyping implicates ADRA1B gene variants in psoriasis susceptibility in a Chinese population. Epigenomics. 2019; :. doi: 10.2217/epi-2018-0131. PubMed PMID:30785334 .
  7. Li, W, Kang, J, Liu, Y, Zhu, M, Li, Y, Qu, J et al.. Extrinsic Two-dimensional Flux Pinning Centers in MgB2 Superconductor Induced by Graphene-Coated Boron. ACS Appl Mater Interfaces. 2019; :. doi: 10.1021/acsami.8b19645. PubMed PMID:30785258 .
  8. Miao, W, Wang, D, Liu, Z, Tang, J, Zhu, Z, Wang, C et al.. Bioinspired Self-Healing Liquid Films for Ultradurable Electronics. ACS Nano. 2019; :. doi: 10.1021/acsnano.8b08911. PubMed PMID:30785255 .
  9. Deng, N, Li, M, Shen, D, He, Q, Sun, W, Liu, M et al.. LRP1 receptor-mediated immunosuppression of α-MMC on monocytes. Int. Immunopharmacol. 2019;70 :80-87. doi: 10.1016/j.intimp.2019.01.036. PubMed PMID:30785094 .
  10. Zhang, Q, Xie, X, Liu, Y, Zheng, X, Wang, Y, Cong, J et al.. Fructose as an additional co-metabolite promotes refractory dye degradation: Performance and mechanism. Bioresour. Technol. 2019;280 :430-440. doi: 10.1016/j.biortech.2019.02.046. PubMed PMID:30784993 .
  11. Yang, B, Wang, N, Wang, S, Li, X, Zheng, Y, Li, M et al.. Network-pharmacology-based identification of caveolin-1 as a key target of Oldenlandia diffusa to suppress breast cancer metastasis. Biomed. Pharmacother. 2019;112 :108607. doi: 10.1016/j.biopha.2019.108607. PubMed PMID:30784915 .
  12. Huang, M, Cheng, J, Chen, P, Zheng, G, Wang, D, Hu, Y et al.. Efficient production of succinic acid in engineered Escherichia coli strains controlled by anaerobically-induced nirB promoter using sweet potato waste hydrolysate. J. Environ. Manage. 2019;237 :147-154. doi: 10.1016/j.jenvman.2019.02.041. PubMed PMID:30784862 .
  13. Zheng, Z, Lang, M, Wang, W, Xiao, F, Li, J. Episodic reconstruction contributes to high-confidence false recognition memories in older adults: Evidence from event-related potentials. Brain Cogn. 2019;132 :13-21. doi: 10.1016/j.bandc.2019.02.002. PubMed PMID:30784854 .
  14. Hao, R, Du, X, Yang, C, Deng, Y, Zheng, Z, Wang, Q et al.. Integrated application of transcriptomics and metabolomics provides insights into unsynchronized growth in pearl oyster Pinctada fucata martensii. Sci. Total Environ. 2019;666 :46-56. doi: 10.1016/j.scitotenv.2019.02.221. PubMed PMID:30784822 .
  15. Dong, W, Wang, F, Fang, M, Wu, J, Wang, S, Li, M et al.. Use of biological detection methods to assess dioxin-like compounds in sediments of Bohai Bay, China. Ecotoxicol. Environ. Saf. 2019;173 :339-346. doi: 10.1016/j.ecoenv.2019.01.116. PubMed PMID:30784797 .
  16. Zhong, W, Xu, M, Li, C, Zhu, B, Cao, X, Li, D et al.. ORP4L Extracts and Presents PIP from Plasma Membrane for PLCβ3 Catalysis: Targeting It Eradicates Leukemia Stem Cells. Cell Rep. 2019;26 (8):2166-2177.e9. doi: 10.1016/j.celrep.2019.01.082. PubMed PMID:30784597 .
  17. Yang, L, Zhao, Y, Shi, M, Zheng, M, Xu, Y, Li, C et al.. Brominated dioxins and furans in a cement kiln co-processing municipal solid waste. J Environ Sci (China). 2019;79 :339-345. doi: 10.1016/j.jes.2018.12.009. PubMed PMID:30784457 .
  18. Yang, Y, Liu, X, Zheng, J, Tan, Q, Feng, M, Qu, Y et al.. Characteristics of one-year observation of VOCs, NOx, and O at an urban site in Wuhan, China. J Environ Sci (China). 2019;79 :297-310. doi: 10.1016/j.jes.2018.12.002. PubMed PMID:30784453 .
  19. Zheng, G, Song, K, Zhao, Y. Liver kinase B1 suppresses the metastasis and angiogenesis of lung cancer: involvement of the Shh signaling pathway. Neoplasma. 2019; :. doi: 10.4149/neo_2018_180820N630. PubMed PMID:30784288 .
  20. Lu, B, Zheng, X, Li, Z. Few-layer PO: A Promising Photocatalyst for Water Splitting. ACS Appl Mater Interfaces. 2019; :. doi: 10.1021/acsami.8b21001. PubMed PMID:30784267 .
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