Johan Gagniere

Johan Gagniere

Johan Gagniere, MD, PhD

 

Profile:

I am studying oncologic outcomes and prognostic factors in BRAF mutant patients undergoing surgery for colorectal liver metastases. I also am studying the utility of a 3D image-guidance system in patients with intraoperative sonographically-occult colorectal liver metastases, and the interest of an intraoperative evaluation of the remnant pancreas perfusion using ICG to predict surgical outcomes after pancreatecomies. I obtained my medical degree from the University of Clermont-Auvergne, France in 2011, and I am now an attending HPB surgeon at the University Hospital of Clermont-Ferrand, France since 3 years. I obtained my Ph.D. degree at the U1071 INSERM unit, Clermont-Ferrand, France in 2017, where I am still working on the interactions between gut microbiota and colorectal cancer.


Funding Info:

1) University Hospital of Clermont-Ferrand Grant, France, for Cancer Research

2) Nuovo Soldati Foundation Grant for Cancer Research


Publications:

  1. Voron, T, Gronnier, C, Pasquer, A, Thereaux, J, Gagniere, J, Lebreton, G et al.. Adenocarcinoma of the oesophagogastric junction Siewert II: An oesophageal cancer better cured with total gastrectomy. Eur J Surg Oncol. 2019; :. doi: 10.1016/j.ejso.2019.07.022. PubMed PMID:31350076 .
  2. Golia Pernicka, JS, Gagniere, J, Chakraborty, J, Yamashita, R, Nardo, L, Creasy, JM et al.. Radiomics-based prediction of microsatellite instability in colorectal cancer at initial computed tomography evaluation. Abdom Radiol (NY). 2019; :. doi: 10.1007/s00261-019-02117-w. PubMed PMID:31250180 .
  3. Sgarbura, O, Hübner, M, Alyami, M, Eveno, C, Gagnière, J, Pache, B et al.. Oxaliplatin use in pressurized intraperitoneal aerosol chemotherapy (PIPAC) is safe and effective: A multicenter study. Eur J Surg Oncol. 2019; :. doi: 10.1016/j.ejso.2019.05.007. PubMed PMID:31092362 .
  4. Bonnot, PE, Piessen, G, Kepenekian, V, Decullier, E, Pocard, M, Meunier, B et al.. Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy for Gastric Cancer With Peritoneal Metastases (CYTO-CHIP study): A Propensity Score Analysis. J. Clin. Oncol. 2019;37 (23):2028-2040. doi: 10.1200/JCO.18.01688. PubMed PMID:31084544 .
  5. Mercier, F, Dagbert, F, Pocard, M, Goéré, D, Quenet, F, Wernert, R et al.. Recurrence of pseudomyxoma peritonei after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. BJS Open. 2019;3 (2):195-202. doi: 10.1002/bjs5.97. PubMed PMID:30957067 PubMed Central PMC6433307.
  6. Pak, LM, Gagnière, J, Allen, PJ, Balachandran, VP, D'Angelica, MI, DeMatteo, RP et al.. Utility of Image Guidance in the Localization of Disappearing Colorectal Liver Metastases. J. Gastrointest. Surg. 2019;23 (4):760-767. doi: 10.1007/s11605-019-04106-2. PubMed PMID:30680630 .
  7. Vogin, G, Hettal, L, Vignaud, JM, Dartigues, P, Goere, D, Ferron, G et al.. Well-Differentiated Papillary Mesothelioma of the Peritoneum: A Retrospective Study from the RENAPE Observational Registry. Ann. Surg. Oncol. 2019;26 (3):852-860. doi: 10.1245/s10434-018-07153-2. PubMed PMID:30635798 .
  8. Rompteaux, P, Gagnière, J, Gornet, JM, Coriat, R, Baumgaertner, I, Lecomte, T et al.. Resection of small bowel adenocarcinoma metastases: Results of the ARCAD-NADEGE cohort study. Eur J Surg Oncol. 2019;45 (3):331-335. doi: 10.1016/j.ejso.2018.11.012. PubMed PMID:30501999 .
  9. Gagnière, J, Le Roy, B, Veziant, J, Pereira, B, Narayan, RR, Pezet, D et al.. Pancreaticoduodenectomy with right gastric vessels preservation: impact on intraoperative and postoperative outcomes. ANZ J Surg. 2019;89 (4):E147-E152. doi: 10.1111/ans.14956. PubMed PMID:30497109 .
  10. Gagnière, J. HIPEC in the Elderly: A Meta-Analysis. Ann. Surg. Oncol. 2018;25 (Suppl 3):701-702. doi: 10.1245/s10434-018-6776-z. PubMed PMID:30242777 .
  11. Le Roy, B, Dupré, A, Gallon, A, Chabrot, P, Gagnière, J, Buc, E et al.. Liver hypertrophy: Underlying mechanisms and promoting procedures before major hepatectomy. J Visc Surg. 2018;155 (5):393-401. doi: 10.1016/j.jviscsurg.2018.03.005. PubMed PMID:30126801 .
  12. Gagnière, J, Dupré, A, Gholami, SS, Pezet, D, Boerner, T, Gönen, M et al.. Is Hepatectomy Justified for BRAF Mutant Colorectal Liver Metastases?: A Multi-institutional Analysis of 1497 Patients. Ann. Surg. 2018; :. doi: 10.1097/SLA.0000000000002968. PubMed PMID:29995686 .
  13. Malgras, B, Gayat, E, Aoun, O, Lo Dico, R, Eveno, C, Pautrat, K et al.. Impact of Combination Chemotherapy in Peritoneal Mesothelioma Hyperthermic Intraperitoneal Chemotherapy (HIPEC): The RENAPE Study. Ann. Surg. Oncol. 2018;25 (11):3271-3279. doi: 10.1245/s10434-018-6631-2. PubMed PMID:29978366 .
  14. Villéger, R, Lopès, A, Veziant, J, Gagnière, J, Barnich, N, Billard, E et al.. Microbial markers in colorectal cancer detection and/or prognosis. World J. Gastroenterol. 2018;24 (22):2327-2347. doi: 10.3748/wjg.v24.i22.2327. PubMed PMID:29904241 PubMed Central PMC6000297.
  15. Zaanan, A, Bouché, O, Benhaim, L, Buecher, B, Chapelle, N, Dubreuil, O et al.. Gastric cancer: French intergroup clinical practice guidelines for diagnosis, treatments and follow-up (SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO). Dig Liver Dis. 2018;50 (8):768-779. doi: 10.1016/j.dld.2018.04.025. PubMed PMID:29886081 .
  16. Courtot, L, Le Roy, B, Memeo, R, Voron, T, de Angelis, N, Tabchouri, N et al.. Risk factors for postoperative ileus following elective laparoscopic right colectomy: a retrospective multicentric study. Int J Colorectal Dis. 2018;33 (10):1373-1382. doi: 10.1007/s00384-018-3070-2. PubMed PMID:29732465 .
  17. Cohen, C, Tessier, W, Gronnier, C, Renaud, F, Pasquer, A, Théreaux, J et al.. Salvage Surgery for Esophageal Cancer: How to Improve Outcomes?. Ann. Surg. Oncol. 2018;25 (5):1277-1286. doi: 10.1245/s10434-018-6365-1. PubMed PMID:29417405 .
  18. Delhorme, JB, Severac, F, Averous, G, Glehen, O, Passot, G, Bakrin, N et al.. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei of appendicular and extra-appendicular origin. Br J Surg. 2018;105 (6):668-676. doi: 10.1002/bjs.10716. PubMed PMID:29412465 .
  19. Gagnière, J, Poston, GJ, Boerner, T, Le Roy, B, Dupré, A. Unresectable Colorectal Liver Metastases: When Definitions Matter to Appropriately Assess Extreme Liver Resection Techniques. Ann. Surg. 2018;268 (6):e82-e83. doi: 10.1097/SLA.0000000000002677. PubMed PMID:29342016 .
  20. Scalabre, A, Philippe-Chomette, P, Passot, G, Orbach, D, Elias, D, Corradini, N et al.. Cytoreductive surgery and hyperthermic intraperitoneal perfusion with chemotherapy in children with peritoneal tumor spread: A French nationwide study over 14 years. Pediatr Blood Cancer. 2018;65 (4):. doi: 10.1002/pbc.26934. PubMed PMID:29286576 .
Search PubMed