Sharon Lawrence

Sharon Lawrence

Sharon Lawrence, MD


I came to the HPB department in July 2016 to focus on pancreas cancer research. To date, I have completed a study examining the outcomes of long-term surveillance of pancreas cysts. We have demonstrated that after 5 years of surveillance, both stable (those without radiographic changes) and unstable cysts can still go on to experience radiographic progression, cross-over to resection, and progression to cancer. I am currently working on studies evaluating the use of quantitative imaging to predict progression of premalignant pancreas cysts to overt malignancy. In addition to these studies, I am conducting a study to evaluate our rates of surgical site infection after Whipple operation, which will be followed by implementation of a perioperative bundle to determine if we can reduce the rate of infections. Prior to my stint at MSKCC, I completed two years of general surgery residency at Rutgers Robert Wood Johnson. I am a graduate of Albert Einstein College of Medicine, and completed my undergraduate studies at MIT.


  1. McIntyre, CA, Pulvirenti, A, Lawrence, SA, Seier, K, Gonen, M, Balachandran, VP et al.. Neutrophil-to-Lymphocyte Ratio as a Predictor of Invasive Carcinoma in Patients With Intraductal Papillary Mucinous Neoplasms of the Pancreas. Pancreas. 2019;48 (6):832-836. doi: 10.1097/MPA.0000000000001342. PubMed PMID:31210665 .
  2. Lawrence, SA, McIntyre, CA, Pulvirenti, A, Seier, K, Chou, Y, Gonen, M et al.. Perioperative Bundle to Reduce Surgical Site Infection after Pancreaticoduodenectomy: A Prospective Cohort Study. J. Am. Coll. Surg. 2019;228 (4):595-601. doi: 10.1016/j.jamcollsurg.2018.12.018. PubMed PMID:30630087 .
  3. Lawrence, SA, Attiyeh, MA, Seier, K, Gönen, M, Schattner, M, Haviland, DL et al.. Should Patients With Cystic Lesions of the Pancreas Undergo Long-term Radiographic Surveillance?: Results of 3024 Patients Evaluated at a Single Institution. Ann. Surg. 2017;266 (3):536-544. doi: 10.1097/SLA.0000000000002371. PubMed PMID:28657939 .
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