Vinod P. Balachandran, MD, FACS

Vinod P. Balachandran, MD, FACS

HPB Service; Assistant Attending

Profile:

Dr. Balachandran is an Assistant Attending Surgeon in the Hepatopancreatobiliary Service in the Department of Surgery at Memorial Sloan Kettering Cancer Center and a member of the David M. Rubenstein Center for Pancreatic Cancer Research. In addition to performing surgeries and caring for patients, he performs laboratory research to identify new ways to use the immune system to fight pancreatic cancer. T cells are highly specialized cells of the immune system designed to protect the human body from infections and cancer. In the past decade, we have discovered that T cells recognize and kill cancers. By understanding how T cells recognize cancer, we have now developed treatments called immunotherapies to supercharge T cells and overcome cancer defenses.

Read more about Dr. Balachandran’s research on immune system among pancreatic cancer long-term survivors on “Why Do Some People Beat the Odds against Pancreatic Cancer?”


Dr. Balachandran’s MSK Profile
Dr. Balachandran’s Lab

Publications:

  1. Buisman, FE, Galjart, B, van der Stok, EP, Balachandran, VP, Boerner, T, Drebin, JA et al.. Recurrence Patterns After Resection of Colorectal Liver Metastasis are Modified by Perioperative Systemic Chemotherapy. World J Surg. 2019; :. doi: 10.1007/s00268-019-05121-9. PubMed PMID:31410513 .
  2. Khalil, DN, Suek, N, Campesato, LF, Budhu, S, Redmond, D, Samstein, RM et al.. In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors. J. Clin. Invest. 2019;129 (8):3435-3447. doi: 10.1172/JCI128562. PubMed PMID:31329159 PubMed Central PMC6668692.
  3. Attiyeh, MA, Chakraborty, J, McIntyre, CA, Kappagantula, R, Chou, Y, Askan, G et al.. CT radiomics associations with genotype and stromal content in pancreatic ductal adenocarcinoma. Abdom Radiol (NY). 2019;44 (9):3148-3157. doi: 10.1007/s00261-019-02112-1. PubMed PMID:31243486 PubMed Central PMC6692205.
  4. McIntyre, CA, Pulvirenti, A, Lawrence, SA, Seier, K, Gonen, M, Balachandran, VP et al.. Neutrophil-to-Lymphocyte Ratio as a Predictor of Invasive Carcinoma in Patients With Intraductal Papillary Mucinous Neoplasms of the Pancreas. Pancreas. 2019;48 (6):832-836. doi: 10.1097/MPA.0000000000001342. PubMed PMID:31210665 .
  5. Creasy, JM, Goldman, DA, Gonen, M, Dudeja, V, O'Reilly, EM, Abou-Alfa, GK et al.. Evolution of surgical management of gallbladder carcinoma and impact on outcome: results from two decades at a single-institution. HPB (Oxford). 2019; :. doi: 10.1016/j.hpb.2019.03.370. PubMed PMID:31027875 .
  6. Cavnar, MJ, Seier, K, Curtin, C, Balachandran, VP, Coit, DG, Yoon, SS et al.. Outcome of 1000 Patients With Gastrointestinal Stromal Tumor (GIST) Treated by Surgery in the Pre and Post-imatinib Eras. Ann. Surg. 2019; :. doi: 10.1097/SLA.0000000000003277. PubMed PMID:30946076 .
  7. Narayan, RR, Goldman, DA, Gonen, M, Reichel, J, Huberman, KH, Raj, S et al.. Peripheral Circulating Tumor DNA Detection Predicts Poor Outcomes After Liver Resection for Metastatic Colorectal Cancer. Ann. Surg. Oncol. 2019;26 (6):1824-1832. doi: 10.1245/s10434-019-07201-5. PubMed PMID:30706231 PubMed Central PMC6511310.
  8. Pak, LM, Gagnière, J, Allen, PJ, Balachandran, VP, D'Angelica, MI, DeMatteo, RP et al.. Utility of Image Guidance in the Localization of Disappearing Colorectal Liver Metastases. J. Gastrointest. Surg. 2019;23 (4):760-767. doi: 10.1007/s11605-019-04106-2. PubMed PMID:30680630 .
  9. Balachandran, VP, Beatty, GL, Dougan, SK. Broadening the Impact of Immunotherapy to Pancreatic Cancer: Challenges and Opportunities. Gastroenterology. 2019;156 (7):2056-2072. doi: 10.1053/j.gastro.2018.12.038. PubMed PMID:30660727 PubMed Central PMC6486864.
  10. Lawrence, SA, McIntyre, CA, Pulvirenti, A, Seier, K, Chou, Y, Gonen, M et al.. Perioperative Bundle to Reduce Surgical Site Infection after Pancreaticoduodenectomy: A Prospective Cohort Study. J. Am. Coll. Surg. 2019;228 (4):595-601. doi: 10.1016/j.jamcollsurg.2018.12.018. PubMed PMID:30630087 .
  11. Narayan, RR, Creasy, JM, Goldman, DA, Gönen, M, Kandoth, C, Kundra, R et al.. Regional differences in gallbladder cancer pathogenesis: Insights from a multi-institutional comparison of tumor mutations. Cancer. 2019;125 (4):575-585. doi: 10.1002/cncr.31850. PubMed PMID:30427539 PubMed Central PMC6636637.
  12. Kunstman, JW, Goldman, DA, Gönen, M, Balachandran, VP, D'Angelica, MI, Kingham, TP et al.. Outcomes after Pancreatectomy with Routine Pasireotide Use. J. Am. Coll. Surg. 2019;228 (2):161-170.e2. doi: 10.1016/j.jamcollsurg.2018.10.018. PubMed PMID:30414453 .
  13. Sadot, E, Zheng, J, Srouji, R, Strong, VE, Gönen, M, Balachandran, VP et al.. Correction to: Hypophosphatemia as a Predictor of Organ-Specific Complications Following Gastrointestinal Surgery: Analysis of 8034 Patients. World J Surg. 2019;43 (2):395. doi: 10.1007/s00268-018-4845-x. PubMed PMID:30406321 .
  14. Attiyeh, MA, Chakraborty, J, Gazit, L, Langdon-Embry, L, Gonen, M, Balachandran, VP et al.. Preoperative risk prediction for intraductal papillary mucinous neoplasms by quantitative CT image analysis. HPB (Oxford). 2019;21 (2):212-218. doi: 10.1016/j.hpb.2018.07.016. PubMed PMID:30097414 PubMed Central PMC6367060.
  15. Tufts, LS, Jarnagin, ED, Flynn, JR, Gonen, M, Guillem, JG, Paty, PB et al.. A perioperative multidisciplinary care bundle reduces surgical site infections in patients undergoing synchronous colorectal and liver resection. HPB (Oxford). 2019;21 (2):181-186. doi: 10.1016/j.hpb.2018.07.001. PubMed PMID:30077525 PubMed Central PMC6358518.
  16. Zheng, J, Sadot, E, Vigidal, JA, Klimstra, DS, Balachandran, VP, Kingham, TP et al.. Characterization of hepatocellular adenoma and carcinoma using microRNA profiling and targeted gene sequencing. PLoS ONE. 2018;13 (7):e0200776. doi: 10.1371/journal.pone.0200776. PubMed PMID:30052636 PubMed Central PMC6063411.
  17. Gagnière, J, Dupré, A, Gholami, SS, Pezet, D, Boerner, T, Gönen, M et al.. Is Hepatectomy Justified for BRAF Mutant Colorectal Liver Metastases?: A Multi-institutional Analysis of 1497 Patients. Ann. Surg. 2018; :. doi: 10.1097/SLA.0000000000002968. PubMed PMID:29995686 .
  18. Sadot, E, Zheng, J, Srouji, R, Strong, VE, Gönen, M, Balachandran, VP et al.. Hypophosphatemia as a Predictor of Organ-Specific Complications Following Gastrointestinal Surgery: Analysis of 8034 Patients. World J Surg. 2019;43 (2):385-394. doi: 10.1007/s00268-018-4726-3. PubMed PMID:29955938 PubMed Central PMC6310662.
  19. Creasy, JM, Midya, A, Chakraborty, J, Adams, LB, Gomes, C, Gonen, M et al.. Quantitative imaging features of pretreatment CT predict volumetric response to chemotherapy in patients with colorectal liver metastases. Eur Radiol. 2019;29 (1):458-467. doi: 10.1007/s00330-018-5542-8. PubMed PMID:29922934 PubMed Central PMC6301122.
  20. Creasy, JM, Sadot, E, Koerkamp, BG, Chou, JF, Gonen, M, Kemeny, NE et al.. Actual 10-year survival after hepatic resection of colorectal liver metastases: what factors preclude cure?. Surgery. 2018;163 (6):1238-1244. doi: 10.1016/j.surg.2018.01.004. PubMed PMID:29455841 .
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